Downregulation of the phosphatase JKAP/DUSP22 in T cells as a potential new biomarker of systemic lupus erythematosus nephritis

Systemic lupus erythematosus (SLE) is a complex autoimmune disease that is characterized by systemic inflammation and multiple organ failures. Dysregulation of T cells plays a critical role in SLE pathogenesis. Our previous study indicates that JKAP (also named DUSP22) inhibits T-cell activation and...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Chuang, Huai-Chia, Chen, Yi-Ming, Hung, Wei-Ting, Li, Ju-Pi, Chen, Der-Yuan, Lan, Joung-Liang, Tan, Tse-Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper: Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295375/
https://ncbi.nlm.nih.gov/pubmed/27557500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11419
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