SHP2, SOCS3 and PIAS3 Expression Patterns in Medulloblastomas: Relevance to STAT3 Activation and Resveratrol-Suppressed STAT3 Signaling

Background: Activated STAT3 signaling is critical for human medulloblastoma cells. SHP2, SOCS3 and PIAS3 are known as the negative regulators of STAT3 signaling, while their relevance to frequent STAT3 activation in medulloblastomas remains unknown. Methods: Tissue microarrays were constructed with...

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Publicado no:Nutrients
Main Authors: Li, Cong, Li, Hong, Zhang, Peng, Yu, Li-Jun, Huang, Tian-Miao, Song, Xue, Kong, Qing-You, Dong, Jian-Li, Li, Pei-Nan, Liu, Jia
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5295047/
https://ncbi.nlm.nih.gov/pubmed/28035977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nu9010003
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