The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8(+) T cells in the tumor microenvironment

Lignende værker

• LAG-3 and 4-1BB identify dysfunctional antigen-specific T cells in the tumor microenvironment and combinatorial LAG-3/4-1BB targeting gives synergistic tumor control
  af: Williams, Jason B, et al.
  Udgivet: (2015)
• Agonistic 4-1bb antibodies in combination with inhibitory antibodies against CTLA-4, PD-L1 or LAG-3 ACT on CD8+ T cells in the tumor microenvironment and synergize to promote regression of established tumors
  af: Horton, Brendan, et al.
  Udgivet: (2014)
• Agonist anti-4-1BB plus neutralizing anti-CTLA-4 or -PD-L1 synergize to promote tumor regression by rescuing dying dysfunctional CD8+ T cells within the tumor microenvironment
  af: Horton, Brendan, et al.
  Udgivet: (2015)
• Egr2 targets identify a population of dysfunctional T cells in the tumor microenvironment with immune modulatory properties
  af: Williams, Jason, et al.
  Udgivet: (2013)
• Egr2 targets identify a population of dysfunctional T cells in the tumor microenvironment with immune modulatory properties
  af: Williams, Jason, et al.
  Udgivet: (2014)