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Shutting down the power supply for DNA repair in cancer cells
Phosphoglycerate mutase 1 (PGAM1) functions in glycolysis. In this issue, Qu et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201607008) show that PGAM1 inactivation leads to nucleotide depletion, which causes defective homologous recombination–mediated DNA repair, suggesting that targeting m...
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| Publicado no: | J Cell Biol |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5294795/ https://ncbi.nlm.nih.gov/pubmed/28122958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201701026 |
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