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Acetylation of insulin receptor substrate-1 is permissive for tyrosine phosphorylation

BACKGROUND: Insulin receptor substrate (IRS) proteins are key moderators of insulin action. Their specific regulation determines downstream protein-protein interactions and confers specificity on growth factor signalling. Regulatory mechanisms that have been identified include phosphorylation of IRS...

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Autori principali: Kaiser, Christina, James, Stephen R
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC529456/
https://ncbi.nlm.nih.gov/pubmed/15522123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7007-2-23
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