Improving the therapeutic efficacy of mesenchymal stromal cells to restore perfusion in critical limb ischemia through pulsed focused ultrasound

Mesenchymal stem cells (MSC) are promising therapeutics for critical limb ischemia (CLI). Mechanotransduction from pulsed focused ultrasound (pFUS) upregulates local chemoattractants to enhance homing of intravenously (IV)-infused MSC and improve outcomes. This study investigated whether pFUS exposu...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Tebebi, Pamela A., Kim, Saejeong J., Williams, Rashida A., Milo, Blerta, Frenkel, Victor, Burks, Scott R., Frank, Joseph A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294408/
https://ncbi.nlm.nih.gov/pubmed/28169278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41550
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