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Improving the therapeutic efficacy of mesenchymal stromal cells to restore perfusion in critical limb ischemia through pulsed focused ultrasound

Mesenchymal stem cells (MSC) are promising therapeutics for critical limb ischemia (CLI). Mechanotransduction from pulsed focused ultrasound (pFUS) upregulates local chemoattractants to enhance homing of intravenously (IV)-infused MSC and improve outcomes. This study investigated whether pFUS exposu...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Tebebi, Pamela A., Kim, Saejeong J., Williams, Rashida A., Milo, Blerta, Frenkel, Victor, Burks, Scott R., Frank, Joseph A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5294408/
https://ncbi.nlm.nih.gov/pubmed/28169278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41550
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