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Acute alloxan renal toxicity in the rat initially causes degeneration of thick ascending limbs of Henle

Alloxan (AL) is a material well-known to induce diabetes. Prior to inducing a prolonged diabetic state, AL causes acute tubulointerstitial nephritis. However, the precise primary target site and mechanism of its nephrotoxicity remain unclear. The objective of this study was to evaluate the morpholog...

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Bibliografiske detaljer
Udgivet i:J Toxicol Pathol
Main Authors: Terayama, Yui, Kodama, Yasushi, Matsuura, Tetsuro, Ozaki, Kiyokazu
Format: Artigo
Sprog:Inglês
Udgivet: Japanese Society of Toxicologic Pathology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293687/
https://ncbi.nlm.nih.gov/pubmed/28190920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2016-0035
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