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Acute alloxan renal toxicity in the rat initially causes degeneration of thick ascending limbs of Henle
Alloxan (AL) is a material well-known to induce diabetes. Prior to inducing a prolonged diabetic state, AL causes acute tubulointerstitial nephritis. However, the precise primary target site and mechanism of its nephrotoxicity remain unclear. The objective of this study was to evaluate the morpholog...
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Publicado no: | J Toxicol Pathol |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Japanese Society of Toxicologic Pathology
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5293687/ https://ncbi.nlm.nih.gov/pubmed/28190920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2016-0035 |
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