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Acute alloxan renal toxicity in the rat initially causes degeneration of thick ascending limbs of Henle

Alloxan (AL) is a material well-known to induce diabetes. Prior to inducing a prolonged diabetic state, AL causes acute tubulointerstitial nephritis. However, the precise primary target site and mechanism of its nephrotoxicity remain unclear. The objective of this study was to evaluate the morpholog...

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Detalhes bibliográficos
Publicado no:J Toxicol Pathol
Main Authors: Terayama, Yui, Kodama, Yasushi, Matsuura, Tetsuro, Ozaki, Kiyokazu
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Society of Toxicologic Pathology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293687/
https://ncbi.nlm.nih.gov/pubmed/28190920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1293/tox.2016-0035
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