Gene Expression Noise Enhances Robust Organization of the Early Mammalian Blastocyst

A critical event in mammalian embryo development is construction of an inner cell mass surrounded by a trophoectoderm (a shell of cells that later form extraembryonic structures). We utilize multi-scale, stochastic modeling to investigate the design principles responsible for robust establishment of...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:PLoS Comput Biol
Main Authors: Holmes, William R., Reyes de Mochel, Nabora Soledad, Wang, Qixuan, Du, Huijing, Peng, Tao, Chiang, Michael, Cinquin, Olivier, Cho, Ken, Nie, Qing
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293272/
https://ncbi.nlm.nih.gov/pubmed/28114387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1005320
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