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Interactome disassembly during apoptosis occurs independent of caspase cleavage

Protein–protein interaction networks (interactomes) define the functionality of all biological systems. In apoptosis, proteolysis by caspases is thought to initiate disassembly of protein complexes and cell death. Here we used a quantitative proteomics approach, protein correlation profiling (PCP),...

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Dettagli Bibliografici
Pubblicato in:Mol Syst Biol
Autori principali: Scott, Nichollas E, Rogers, Lindsay D, Prudova, Anna, Brown, Nat F, Fortelny, Nikolaus, Overall, Christopher M, Foster, Leonard J
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293159/
https://ncbi.nlm.nih.gov/pubmed/28082348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20167067
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