Interactome disassembly during apoptosis occurs independent of caspase cleavage

Protein–protein interaction networks (interactomes) define the functionality of all biological systems. In apoptosis, proteolysis by caspases is thought to initiate disassembly of protein complexes and cell death. Here we used a quantitative proteomics approach, protein correlation profiling (PCP),...

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Bibliographic Details
Published in:Mol Syst Biol
Main Authors: Scott, Nichollas E, Rogers, Lindsay D, Prudova, Anna, Brown, Nat F, Fortelny, Nikolaus, Overall, Christopher M, Foster, Leonard J
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2017
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293159/
https://ncbi.nlm.nih.gov/pubmed/28082348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20167067
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