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Interactome disassembly during apoptosis occurs independent of caspase cleavage

Protein–protein interaction networks (interactomes) define the functionality of all biological systems. In apoptosis, proteolysis by caspases is thought to initiate disassembly of protein complexes and cell death. Here we used a quantitative proteomics approach, protein correlation profiling (PCP),...

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Podrobná bibliografie
Vydáno v:Mol Syst Biol
Hlavní autoři: Scott, Nichollas E, Rogers, Lindsay D, Prudova, Anna, Brown, Nat F, Fortelny, Nikolaus, Overall, Christopher M, Foster, Leonard J
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293159/
https://ncbi.nlm.nih.gov/pubmed/28082348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20167067
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