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Early commitment and robust differentiation in colonic crypts
Tissue stem cells produce a constant flux of differentiated cells with distinct proportions. Here, we show that stem cells in colonic crypts differentiate early to form precisely 1:3 ratio of secretory to absorptive cells. This precision is surprising, as there are only eight stem cells making irrev...
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| Udgivet i: | Mol Syst Biol |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5293156/ https://ncbi.nlm.nih.gov/pubmed/28049136 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20167283 |
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