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Protein abundance of AKT and ERK pathway components governs cell type‐specific regulation of proliferation

Signaling through the AKT and ERK pathways controls cell proliferation. However, the integrated regulation of this multistep process, involving signal processing, cell growth and cell cycle progression, is poorly understood. Here, we study different hematopoietic cell types, in which AKT and ERK sig...

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Detalhes bibliográficos
Publicado no:Mol Syst Biol
Main Authors: Adlung, Lorenz, Kar, Sandip, Wagner, Marie‐Christine, She, Bin, Chakraborty, Sajib, Bao, Jie, Lattermann, Susen, Boerries, Melanie, Busch, Hauke, Wuchter, Patrick, Ho, Anthony D, Timmer, Jens, Schilling, Marcel, Höfer, Thomas, Klingmüller, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293153/
https://ncbi.nlm.nih.gov/pubmed/28123004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/msb.20167258
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