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Unlocking Tn3-family transposase activity in vitro unveils an asymetric pathway for transposome assembly
The Tn3 family is a widespread group of replicative transposons that are notorious for their contribution to the dissemination of antibiotic resistance and the emergence of multiresistant pathogens worldwide. The TnpA transposase of these elements catalyzes DNA breakage and rejoining reactions requi...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5293067/ https://ncbi.nlm.nih.gov/pubmed/28096365 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1611701114 |
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