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α-Actinin/titin interaction: A dynamic and mechanically stable cluster of bonds in the muscle Z-disk
Stable anchoring of titin within the muscle Z-disk is essential for preserving muscle integrity during passive stretching. One of the main candidates for anchoring titin in the Z-disk is the actin cross-linker α-actinin. The calmodulin-like domain of α-actinin binds to the Z-repeats of titin. Howeve...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5293040/ https://ncbi.nlm.nih.gov/pubmed/28096424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612681114 |
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