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Polyspecific Organic Cation Transporters and their Impact on Drug Intracellular Levels and Pharmacodynamics

Most drugs are intended to act on molecular targets residing within a specific tissue or cell type. Therefore, the drug concentration within the target tissue or cells is most relevant to its pharmacological effect. Increasing evidences suggest that drug transporters not only play a significant role...

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Detalhes bibliográficos
Publicado no:Pharmacol Res
Main Authors: Wagner, David J., Hu, Tao, Wang, Joanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5293005/
https://ncbi.nlm.nih.gov/pubmed/27317943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.phrs.2016.06.002
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