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Characterization of Meta-Iodobenzylguanidine (mIBG) Transport by Polyspecific Organic Cation Transporters: Implication for mIBG Therapy

Radiolabeled meta-iodobenzylguanidine (mIBG) is an important radiopharmaceutical used in the diagnosis and treatment of neuroendocrine cancers. mIBG is known to enter tumor cells through the norepinephrine transporter. Whole-body scintigraphy has shown rapid mIBG elimination through the kidney and h...

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Bibliografski detalji
Izdano u:Mol Pharmacol
Glavni autori: López Quiñones, Antonio J., Wagner, David J., Wang, Joanne
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Pharmacology and Experimental Therapeutics 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7330676/
https://ncbi.nlm.nih.gov/pubmed/32487736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.120.119495
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