Restenosis Inhibition and Re-differentiation of TGFβ/Smad3-activated Smooth Muscle Cells by Resveratrol

To date, there is no periadventitial drug delivery method available in the clinic to prevent restenotic failure of open vascular reconstructions. Resveratrol is a promising anti-restenotic natural drug but subject to low bioavailability when systemically administered. In order to reconcile these two...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Zhu, Yichen, Takayama, Toshio, Wang, Bowen, Kent, Alycia, Zhang, Mengxue, Binder, Bernard Y.K., Urabe, Go, Shi, Yatao, DiRenzo, Daniel, Goel, Shakti A., Zhou, Yifan, Little, Christopher, Roenneburg, Drew A., Shi, Xu Dong, Li, Lingjun, Murphy, William L., Kent, K. Craig, Ke, Jianjuan, Guo, Lian-Wang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292946/
https://ncbi.nlm.nih.gov/pubmed/28165488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41916
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