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GLUT4 glucose transporter deficiency increases hepatic lipid production and peripheral lipid utilization
A critical defect in type 2 diabetes is impaired insulin-stimulated glucose transport and metabolism in muscle and adipocytes. To understand the metabolic adaptations this elicits, we generated mice with targeted disruption of the GLUT4 glucose transporter in both adipocytes and muscle (AMG4KO). In...
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| Main Authors: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Clinical Investigation
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC529279/ https://ncbi.nlm.nih.gov/pubmed/15578099 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200421341 |
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