Microbial Typing by Machine Learned DNA Melt Signatures

There is still an ongoing demand for a simple broad-spectrum molecular diagnostic assay for pathogenic bacteria. For this purpose, we developed a single-plex High Resolution Melt (HRM) assay that generates complex melt curves for bacterial identification. Using internal transcribed spacer (ITS) regi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Andini, Nadya, Wang, Bo, Athamanolap, Pornpat, Hardick, Justin, Masek, Billie J., Thair, Simone, Hu, Anne, Avornu, Gideon, Peterson, Stephen, Cogill, Steven, Rothman, Richard E., Carroll, Karen C., Gaydos, Charlotte A., Wang, Jeff Tza-Huei, Batzoglou, Serafim, Yang, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292719/
https://ncbi.nlm.nih.gov/pubmed/28165067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep42097
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