Nested Machine Learning Facilitates Increased Sequence Content for Large-Scale Automated High Resolution Melt Genotyping

High Resolution Melt (HRM) is a versatile and rapid post-PCR DNA analysis technique primarily used to differentiate sequence variants among only a few short amplicons. We recently developed a one-vs-one support vector machine algorithm (OVO SVM) that enables the use of HRM for identifying numerous s...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Fraley, Stephanie I., Athamanolap, Pornpat, Masek, Billie J., Hardick, Justin, Carroll, Karen C., Hsieh, Yu-Hsiang, Rothman, Richard E., Gaydos, Charlotte A., Wang, Tza-Huei, Yang, Samuel
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4726007/
https://ncbi.nlm.nih.gov/pubmed/26778280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19218
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