Polymorphism in Plasmodium falciparum Drug Transporter Proteins and Reversal of In Vitro Chloroquine Resistance by a 9,10-Dihydroethanoanthracene Derivative

BG958 reverses resistance in chloroquine-resistant isolates from different countries. Five mutations in the Plasmodium falciparum crt (pfcrt) gene resulting in the amino acid changes K76T, M74I, N75E, A220S, and R371I are systematically identified in resistance-reversed Asian, African, and Brazilian...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Millet, Julie, Alibert, Sandrine, Torrentino-Madamet, Marylin, Rogier, Christophe, Santelli-Rouvier, Christiane, Bigot, Patricia, Mosnier, Joel, Baret, Eric, Barbe, Jacques, Parzy, Daniel, Pradines, Bruno
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2004
Aiheet:
Mechanisms of Action: Physiological Effects
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC529231/
https://ncbi.nlm.nih.gov/pubmed/15561869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.12.4869-4872.2004
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia