Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice

How genetic variations in the dopamine transporter (DAT) combined with exposure to environmental toxins modulate the risk of Parkinson’s disease (PD) remains unclear. Using unbiased stereology in DAT knock-down mice (DAT-KD) and wild-type (WT) littermates we found that decreased DAT caused a loss of...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Neurobiol Aging
Auteurs principaux: Richter, Franziska, Gabby, Lauryn, McDowell, Kimberly A., Mulligan, Caitlyn K., De La Rosa, Krystal, Sioshansi, Pedrom C., Mortazavi, Farzad, Cely, Ingrid, Ackerson, Larry C., Tsan, Linda, Murphy, Niall P., Maidment, Nigel T., Chesselet, Marie-Françoise
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292275/
https://ncbi.nlm.nih.gov/pubmed/28038352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.11.015
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires