Effects of decreased dopamine transporter levels on nigrostriatal neurons and paraquat/maneb toxicity in mice

How genetic variations in the dopamine transporter (DAT) combined with exposure to environmental toxins modulate the risk of Parkinson’s disease (PD) remains unclear. Using unbiased stereology in DAT knock-down mice (DAT-KD) and wild-type (WT) littermates we found that decreased DAT caused a loss of...

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Publicado no:Neurobiol Aging
Main Authors: Richter, Franziska, Gabby, Lauryn, McDowell, Kimberly A., Mulligan, Caitlyn K., De La Rosa, Krystal, Sioshansi, Pedrom C., Mortazavi, Farzad, Cely, Ingrid, Ackerson, Larry C., Tsan, Linda, Murphy, Niall P., Maidment, Nigel T., Chesselet, Marie-Françoise
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5292275/
https://ncbi.nlm.nih.gov/pubmed/28038352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2016.11.015
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