Impact of High-Inoculum Staphylococcus aureus on the Activities of Nafcillin, Vancomycin, Linezolid, and Daptomycin, Alone and in Combination with Gentamicin, in an In Vitro Pharmacodynamic Model

We evaluated the impact of high (9.5 log(10) CFU/g) and moderate (5.5 log(10) CFU/g) inocula of methicillin-susceptible and -resistant Staphylococcus aureus (MSSA and MRSA, respectively) on the activities of nafcillin, linezolid, vancomycin, and daptomycin, alone and in combination with gentamicin i...

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Main Authors: LaPlante, Kerry L., Rybak, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2004
Assuntos:
Clinical Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC529225/
https://ncbi.nlm.nih.gov/pubmed/15561842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.12.4665-4672.2004
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