Impact of High-Inoculum Staphylococcus aureus on the Activities of Nafcillin, Vancomycin, Linezolid, and Daptomycin, Alone and in Combination with Gentamicin, in an In Vitro Pharmacodynamic Model

We evaluated the impact of high (9.5 log(10) CFU/g) and moderate (5.5 log(10) CFU/g) inocula of methicillin-susceptible and -resistant Staphylococcus aureus (MSSA and MRSA, respectively) on the activities of nafcillin, linezolid, vancomycin, and daptomycin, alone and in combination with gentamicin i...

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Autores principales: LaPlante, Kerry L., Rybak, Michael J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2004
Materias:
Clinical Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC529225/
https://ncbi.nlm.nih.gov/pubmed/15561842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.12.4665-4672.2004
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