Docosahexaenoic acid-mediated protein aggregates may reduce proteasome activity and delay myotube degradation during muscle atrophy in vitro

Proteasomes are the primary degradation machinery for oxidatively damaged proteins that compose a class of misfolded protein substrates. Cellular levels of reactive oxygen species increase with age and this cellular propensity is particularly harmful when combined with the age-associated development...

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Detalhes bibliográficos
Publicado no:Exp Mol Med
Main Authors: Shin, Seung Kyun, Kim, Ji Hyeon, Lee, Jung Hoon, Son, Young Hoon, Lee, Min Wook, Kim, Hak Joong, Noh, Sue Ah, Kim, Kwang Pyo, Kim, In-Gyu, Lee, Min Jae
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291838/
https://ncbi.nlm.nih.gov/pubmed/28104914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2016.133
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