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TWEAK causes myotube atrophy through coordinated activation of ubiquitin-proteasome system, autophagy, and caspases
Proinflammatory cytokine TWEAK has now emerged as a key mediator of skeletal muscle-wasting in many catabolic conditions. However, the mechanisms by which TWEAK induces muscle proteolysis remain poorly understood. Here, we have investigated the role of ubiquitin-proteasome system, autophagy, and cas...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4154369/ https://ncbi.nlm.nih.gov/pubmed/21567392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22821 |
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