Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a form of progressive interstitial lung disease with unknown etiology. Due to a lack of effective treatment, IPF is associated with a high mortality rate. The hallmark feature of this disease is the accumulation of activated myofibroblasts that excessively depo...

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Pubblicato in:Cell Stem Cell
Autori principali: Agha, Elie El, Moiseenko, Alena, Kheirollahi, Vahid, De Langhe, Stijn, Crnkovic, Slaven, Kwapiszewska, Grazyna, Kosanovic, Djuro, Schwind, Felix, Schermuly, Ralph T., Henneke, Ingrid, MacKenzie, BreAnne, Quantius, Jennifer, Herold, Susanne, Ntokou, Aglaia, Ahlbrecht, Katrin, Morty, Rory E., Günther, Andreas, Seeger, Werner, Bellusci, Saverio
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291816/
https://ncbi.nlm.nih.gov/pubmed/27867035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.10.004
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