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Two-Way Conversion between Lipogenic and Myogenic Fibroblastic Phenotypes Marks the Progression and Resolution of Lung Fibrosis

Idiopathic pulmonary fibrosis (IPF) is a form of progressive interstitial lung disease with unknown etiology. Due to a lack of effective treatment, IPF is associated with a high mortality rate. The hallmark feature of this disease is the accumulation of activated myofibroblasts that excessively depo...

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Vydáno v:Cell Stem Cell
Hlavní autoři: Agha, Elie El, Moiseenko, Alena, Kheirollahi, Vahid, De Langhe, Stijn, Crnkovic, Slaven, Kwapiszewska, Grazyna, Kosanovic, Djuro, Schwind, Felix, Schermuly, Ralph T., Henneke, Ingrid, MacKenzie, BreAnne, Quantius, Jennifer, Herold, Susanne, Ntokou, Aglaia, Ahlbrecht, Katrin, Morty, Rory E., Günther, Andreas, Seeger, Werner, Bellusci, Saverio
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291816/
https://ncbi.nlm.nih.gov/pubmed/27867035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2016.10.004
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