The predominant form of the amyloid beta-protein precursor in human brain is protease nexin 2.

The amyloid beta protein and the amyloid beta-protein precursor (APP) are major constituents of senile plaques and cerebrovascular deposits in patients with Alzheimer disease and Down syndrome. Most human tissues contain mRNA that encodes forms of APP that contain the Kunitz protease inhibitor (KPI+...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Van Nostrand, W E, Farrow, J S, Wagner, S L, Bhasin, R, Goldgaber, D, Cotman, C W, Cunningham, D D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1991
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52916/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1946448/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.22.10302
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