Yes1 signaling mediates the resistance to Trastuzumab/Lap atinib in breast cancer

BACKGROUND: Overexpression of human epidermal growth factor receptor 2 (HER2) is observed in approximately 15–23% of breast cancers and these cancers are classified as HER2-positive breast cancer. Trastuzumab is the first-line targeted therapeutic drug for HER2-positive breast cancer and has improve...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Takeda, Tatsuaki, Yamamoto, Hiromasa, Kanzaki, Hirotaka, Suzawa, Ken, Yoshioka, Takahiro, Tomida, Shuta, Cui, Xiaojiang, Murali, Ramachandran, Namba, Kei, Sato, Hiroki, Torigoe, Hidejiro, Watanabe, Mototsugu, Shien, Kazuhiko, Soh, Junichi, Asano, Hiroaki, Tsukuda, Kazunori, Kitamura, Yoshihisa, Miyoshi, Shinichiro, Sendo, Toshiaki, Toyooka, Shinichi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291431/
https://ncbi.nlm.nih.gov/pubmed/28158234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171356
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