Analysis of TRPV channel activation by stimulation of FCεRI and MRGPR receptors in mouse peritoneal mast cells

The activation of mast cells (MC) is part of the innate and adaptive immune responses and depends on Ca(2+) entry across the plasma membrane, leading to the release of preformed inflammatory mediators by degranulation or by de novo synthesis. The calcium conducting channels of the TRPV family, known...

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Udgivet i:PLoS One
Main Authors: Solís-López, A., Kriebs, U., Marx, A., Mannebach, S., Liedtke, W. B., Caterina, M. J., Freichel, M., Tsvilovskyy, V. V.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291405/
https://ncbi.nlm.nih.gov/pubmed/28158279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171366
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