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Quantitative modeling of gene expression using DNA shape features of binding sites

Prediction of gene expression levels driven by regulatory sequences is pivotal in genomic biology. A major focus in transcriptional regulation is sequence-to-expression modeling, which interprets the enhancer sequence based on transcription factor concentrations and DNA binding specificities and pre...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Peng, Pei-Chen, Sinha, Saurabh
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291265/
https://ncbi.nlm.nih.gov/pubmed/27257066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw446
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