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Two p53 tetramers bind one consensus DNA response element

p53 tumor suppressor is a transcription factor that controls cell cycle and genetic integrity. In response to genotoxic stress p53 activates DNA repair, cell cycle arrest, apoptosis or senescence, which are initiated via p53 binding to its specific DNA response elements (RE). The consensus p53 DNA R...

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書目詳細資料
發表在:Nucleic Acids Res
Main Authors: Kearns, Sinéad, Lurz, Rudi, Orlova, Elena V., Okorokov, Andrei L.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291249/
https://ncbi.nlm.nih.gov/pubmed/27034469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw215
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