Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells

Idiopathic Pulmonary Fibrosis (IPF) is a progressive, irreversible lung disease with complex pathophysiology. Evidence of endoplasmic reticulum (ER) stress has been reported in alveolar epithelial cells (AEC) in IPF patients. Secreted mediators from bone marrow stem cells (BMSC-cm) have regenerative...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Nita, Izabela, Hostettler, Katrin, Tamo, Luca, Medová, Michaela, Bombaci, Giuseppe, Zhong, Jun, Allam, Ramanjaneyulu, Zimmer, Yitzhak, Roth, Michael, Geiser, Thomas, Gazdhar, Amiq
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291222/
https://ncbi.nlm.nih.gov/pubmed/28157203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41901
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