Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells

Idiopathic Pulmonary Fibrosis (IPF) is a progressive, irreversible lung disease with complex pathophysiology. Evidence of endoplasmic reticulum (ER) stress has been reported in alveolar epithelial cells (AEC) in IPF patients. Secreted mediators from bone marrow stem cells (BMSC-cm) have regenerative...

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Pubblicato in:Sci Rep
Autori principali: Nita, Izabela, Hostettler, Katrin, Tamo, Luca, Medová, Michaela, Bombaci, Giuseppe, Zhong, Jun, Allam, Ramanjaneyulu, Zimmer, Yitzhak, Roth, Michael, Geiser, Thomas, Gazdhar, Amiq
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291222/
https://ncbi.nlm.nih.gov/pubmed/28157203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41901
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