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Hepatocyte growth factor secreted by bone marrow stem cell reduce ER stress and improves repair in alveolar epithelial II cells

Idiopathic Pulmonary Fibrosis (IPF) is a progressive, irreversible lung disease with complex pathophysiology. Evidence of endoplasmic reticulum (ER) stress has been reported in alveolar epithelial cells (AEC) in IPF patients. Secreted mediators from bone marrow stem cells (BMSC-cm) have regenerative...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nita, Izabela, Hostettler, Katrin, Tamo, Luca, Medová, Michaela, Bombaci, Giuseppe, Zhong, Jun, Allam, Ramanjaneyulu, Zimmer, Yitzhak, Roth, Michael, Geiser, Thomas, Gazdhar, Amiq
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5291222/
https://ncbi.nlm.nih.gov/pubmed/28157203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41901
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