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Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance
[Image: see text] Targeting organelles by modulating the redox potential of mitochondria is a promising approach to kill cancer cells that minimizes acquired drug resistance. However, it lacks selectivity because mitochondria perform essential functions for (almost) all cells. We show that enzyme-in...
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| Udgivet i: | J Am Chem Soc |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Chemical
Society
2016
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| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5291163/ https://ncbi.nlm.nih.gov/pubmed/27960313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.6b09783 |
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