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Specific lysis of human immunodeficiency virus type 1-infected cells by a HLA-A3.1-restricted CD8+ cytotoxic T-lymphocyte clone that recognizes a conserved peptide sequence within the gp41 subunit of the envelope protein.

A HLA-A3.1-restricted CD8+ cytotoxic T-cell clone, E7.20, that lyses cells infected with human immunodeficiency virus type 1 was isolated from an infected individual. The epitope was localized to amino acids 768-778 (RLRDLLLIVTR, NL43 env sequence) of the cytoplasmic domain of gp41 by successive use...

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Enregistré dans:
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Takahashi, K, Dai, L C, Fuerst, T R, Biddison, W E, Earl, P L, Moss, B, Ennis, F A
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1991
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC52911/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1719555/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.22.10277
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