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Truncation of Fibronectin-Binding Proteins in Staphylococcus aureus Strain Newman Leads to Deficient Adherence and Host Cell Invasion Due to Loss of the Cell Wall Anchor Function

Staphylococcus aureus fibronectin-binding proteins (FnBPs) play a critical role in S. aureus pathogenesis. FnBPs mediate adhesion to fibronectin and invasion of mammalian cells, including epithelial, endothelial, and fibroblastic cells, by fibronectin bridging to the host cell fibronectin receptor i...

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Udgivet i:Infect Immun
Principais autores: Grundmeier, Matthias, Hussain, Muzaffar, Becker, Petra, Heilmann, Christine, Peters, Georg, Sinha, Bhanu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2004
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529102/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15557640/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.72.12.7155-7163.2004
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