Truncation of Fibronectin-Binding Proteins in Staphylococcus aureus Strain Newman Leads to Deficient Adherence and Host Cell Invasion Due to Loss of the Cell Wall Anchor Function

Staphylococcus aureus fibronectin-binding proteins (FnBPs) play a critical role in S. aureus pathogenesis. FnBPs mediate adhesion to fibronectin and invasion of mammalian cells, including epithelial, endothelial, and fibroblastic cells, by fibronectin bridging to the host cell fibronectin receptor i...

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Detalhes bibliográficos
Main Authors: Grundmeier, Matthias, Hussain, Muzaffar, Becker, Petra, Heilmann, Christine, Peters, Georg, Sinha, Bhanu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Molecular Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC529102/
https://ncbi.nlm.nih.gov/pubmed/15557640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.72.12.7155-7163.2004
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