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Defective membrane expression of human growth hormone (GH) receptor causes Laron-type GH insensitivity syndrome.

Mutations in the growth hormone receptor (GHR) gene can cause growth hormone (GH) resistance. Given the sequence homology between the extracellular domain of the GHR and a soluble GH-binding protein (GH-BP), it is remarkable that GH-BP binding activity is absent from the serum of patients with Laron...

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Détails bibliographiques
Auteurs principaux: Duquesnoy, P, Sobrier, M L, Amselem, S, Goossens, M
Format: Artigo
Langue:Inglês
Publié: 1991
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC52910/
https://ncbi.nlm.nih.gov/pubmed/1719554
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