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Structure of the Lipid Nanodisc-reconstituted Vacuolar ATPase Proton Channel: DEFINITION OF THE INTERACTION OF ROTOR AND STATOR AND IMPLICATIONS FOR ENZYME REGULATION BY REVERSIBLE DISSOCIATION

Eukaryotic vacuolar H(+)-ATPase (V-ATPase) is a multisubunit enzyme complex that acidifies subcellular organelles and the extracellular space. V-ATPase consists of soluble V(1)-ATPase and membrane-integral V(o) proton channel sectors. To investigate the mechanism of V-ATPase regulation by reversible...

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Pubblicato in:J Biol Chem
Autori principali: Stam, Nicholas J., Wilkens, Stephan
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290949/
https://ncbi.nlm.nih.gov/pubmed/27965356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.766790
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