טוען...
The Phosphatidylinositol 3,4,5-trisphosphate (PI(3,4,5)P(3)) Binder Rasa3 Regulates Phosphoinositide 3-kinase (PI3K)-dependent Integrin α(IIb)β(3) Outside-in Signaling
The class I PI3K family of lipid kinases plays an important role in integrin α(IIb)β(3) function, thereby supporting thrombus growth and consolidation. Here, we identify Ras/Rap1GAP Rasa3 (GAP1(IP4BP)) as a major phosphatidylinositol 3,4,5-trisphosphate-binding protein in human platelets and a key r...
שמור ב:
| הוצא לאור ב: | J Biol Chem |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Biochemistry and Molecular Biology
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5290945/ https://ncbi.nlm.nih.gov/pubmed/27903653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.746867 |
| תגים: |
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