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Vibrio cholerae Strains with Mutations in an Atypical Type I Secretion System Accumulate RTX Toxin Intracellularly
This study shows that the Vibrio cholerae RTX toxin is secreted by a four-component type I secretion system (TISS) encoded by rtxB, rtxD, rtxE, and tolC. ATP-binding site mutations in both RtxB and RtxE blocked secretion, demonstrating that this atypical TISS requires two transport ATPases that may...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC529086/ https://ncbi.nlm.nih.gov/pubmed/15547287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.186.23.8137-8143.2004 |
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