Identification of a Vibrio cholerae RTX toxin gene cluster that is tightly linked to the cholera toxin prophage

We identify and characterize a gene cluster in El Tor Vibrio cholerae that encodes a cytotoxic activity for HEp-2 cells in vitro. This gene cluster contains four genes and is physically linked to the cholera toxin (CTX) element in the V. cholerae genome. We demonstrate by using insertional mutagenes...

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Detalhes bibliográficos
Main Authors: Lin, Wei, Fullner, Karla Jean, Clayton, Rebecca, Sexton, Jessica A., Rogers, Marc B., Calia, Kerstin E., Calderwood, Stephen B., Fraser, Claire, Mekalanos, John J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC15352/
https://ncbi.nlm.nih.gov/pubmed/9927695
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