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Surface mediated cooperative interactions of drugs enhance mechanical forces for antibiotic action

The alarming increase of pathogenic bacteria that are resistant to multiple antibiotics is now recognized as a major health issue fuelling demand for new drugs. Bacterial resistance is often caused by molecular changes at the bacterial surface, which alter the nature of specific drug-target interact...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Ndieyira, Joseph W., Bailey, Joe, Patil, Samadhan B., Vögtli, Manuel, Cooper, Matthew A., Abell, Chris, McKendry, Rachel A., Aeppli, Gabriel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290737/
https://ncbi.nlm.nih.gov/pubmed/28155918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep41206
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