A Tel1/MRX-Dependent Checkpoint Inhibits the Metaphase-to-Anaphase Transition after UV Irradiation in the Absence of Mec1

In Saccharomyces cerevisiae, Mec1/ATR plays a primary role in sensing and transducing checkpoint signals in response to different types of DNA lesions, while the role of the Tel1/ATM kinase in DNA damage checkpoints is not as well defined. We found that UV irradiation in G(1) in the absence of Mec1...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Clerici, Michela, Baldo, Veronica, Mantiero, Davide, Lottersberger, Francisca, Lucchini, Giovanna, Longhese, Maria Pia
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2004
Schlagworte:
DNA Dynamics and Chromosome Structure
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC529042/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15542824/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.24.23.10126-10144.2004
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