Endogenous Protein Interactome of Human UDP-Glucuronosyltransferases Exposed by Untargeted Proteomics

The conjugative metabolism mediated by UDP-glucuronosyltransferase enzymes (UGTs) significantly influences the bioavailability and biological responses of endogenous molecule substrates and xenobiotics including drugs. UGTs participate in the regulation of cellular homeostasis by limiting stress ind...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Rouleau, Michèle, Audet-Delage, Yannick, Desjardins, Sylvie, Rouleau, Mélanie, Girard-Bock, Camille, Guillemette, Chantal
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2017
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290407/
https://ncbi.nlm.nih.gov/pubmed/28217095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00023
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