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Stem cell derived interneuron transplants as a treatment for schizophrenia: preclinical validation in a rodent model

An increasing literature suggests that schizophrenia is associated with a reduction in hippocampal interneuron function. Thus, we posit that stem cell-derived interneuron transplants may be an effective therapeutic strategy to reduce hippocampal hyperactivity and attenuate behavioral deficits in sch...

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Publicat a:Mol Psychiatry
Autors principals: Donegan, Jennifer J., Tyson, Jennifer A., Branch, Sarah Y., Beckstead, Michael J., Anderson, Stewart A., Lodge, Daniel J.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5290293/
https://ncbi.nlm.nih.gov/pubmed/27480492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.121
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